Lillian Chong's NIH award renewed for simulating biological processes

Prof. Lillian Chong has been awarded an NIH RO1 renewal for $1.1 million over 4 years to pursue efforts involving "High-Performance Weighted Ensemble Software for Simulation of Complex Bio-Events." The efforts will be carried out in collaboration with co-PI Prof. Daniel Zuckerman (Oregon Health & Science University), co-I Prof. James Faeder (University of Pittsburgh Medical School), and co-I David Aristoff (Colorado State University). 

They have been able to demonstrate the power of the weighted ensemble (WE) strategy in enabling explicit-solvent MD simulation of a protein–protein binding process. Their results provide a number of insights regarding the binding mechanism that cannot be obtained by laboratory experiments.

Congratulations Dr. Chong!