van Stipdonk and Corcovilos Publishes in Rapid Communications in Mass Spectrometry

  • By Jennifer Zheng
  • 1 March 2022

Congratulations to Michael van Stipdonk, Theodore Corcovilos, and their research group for recently publishing their paper, "Intrinsic reactivity of [OUCH]+: Apparent synthesis of [OUS]+ by reaction with CS2" in Rapid Communications in Mass Spectrometry. Read the abstract below!

Abstract: 

Rationale
Building on our report that collision-induced dissociation (CID) can be used to create the highly reactive U-alkylidyne species [O=U≡CH]+, our goal was to determine whether the species could be as an intermediate for synthesis of [OUS]+ by reaction with carbon disulfide (CS2).

Methods
Cationic uranyl-propiolate precursor ions were generated by electrospray ionization, and multiple-stage CID in a linear trap instrument was used to prepare [O=U≡CH]+. Neutral CS2 was admitted into the trap through a modified He inlet and precision leak valves.

Results
The [O=U≡CH]+ ion reacts with CS2 to generate [OUS]+. CID of [OUS]+ causes elimination of the axial sulfide ligand to generate [OU]+. Using isotopically labeled reagent, we found that [OUS]+ reacts with O2 to create [UO2]+.

Conclusions
[O=U≡CH]+ proves to be a useful reagent ion for synthesis of [OUS]+, a species that to date has only been created by gas-phase reactions of U+ and U2+. Dissociation of [OUS]+ to create [OU]+, but not [US]+, and the efficient conversion of the species into [UO2]+, is consistent with the relative differences in U–O and U–S bond energies.