In May of 2016, the Director of NSF unveiled Big Ideas, developed to answer important societal problems while building the transdisciplinary portfolio of focused fundamental research over the next decade. One of these ideas, "Quantum Leap", advances quantum technologies of the future: quantum communication, quantum computing, quantum sensors and quantum simulators. The powerful language provided by quantum mechanics almost a century ago becomes the foundation upon which to build new industries. This process, sometimes called "the second quantum revolution" is marked by the development of practical and marketable solutions for quantum technologies. This Dear Colleague Letter (DCL) is intended to challenge the fundamental research community to achieve the transformative experimental realization of topological quantum computing.